National Medical Products Administration issued the Technical Guiding Principles for Clinical Research and Development of Bispecific Antibody Antitumor Drugs.

CCTV News:National Medical Products Administration website reported on November 14th that recently, National Medical Products Administration Drug Administration Center issued the "Guiding Principles for Clinical Research and Development of bispecific antibody Antitumor Drugs", which pointed out that Bispecific Antibody (BsAb) is an artificial antibody prepared by cell fusion, recombinant DNA, protein engineering and other technologies, which can specifically bind two antigens or two different epitopes of the same antigen at the same time or successively. According to the Guiding Principles, BsAb is different from the single targeting of monoclonal antibodies, and it can play a special biological function such as stimulating directed immune response by combining different epitopes, solve the treatment problems that monoclonal antibodies can’t solve, and bring patients clinical benefits that monoclonal antibodies don’t have. Therefore, in the process of clinical research and development, in addition to following the general research and development rules of anti-tumor drugs, we should also pay attention to clinical value-oriented, based on structural and mechanism characteristics, reasonably determine the research and development topics, and deeply explore, analyze and clarify the clinical advantages of BsAb during the research and development process.

How and why tornadoes form? What to do when encountering tornadoes? What direction to escape and self-help skills?

  How and why tornadoes form? What to do when encountering tornadoes? What direction to escape and self-help skills?

  How is a tornado caused? How to save yourself when encountering a tornado? The reason for the formation of tornado is that the temperature difference between the upper and lower clouds is too large, resulting in a small vortex in which cold air drops and hot air rises; At this time, pieces of cotton-like white clouds appear in the air, which are called cumulus clouds. Then, cumulus clouds continue to develop in the maelstrom to form cumulonimbus clouds, and the latent heat inside the cumulonimbus clouds continues to heat up, thus generating a powerful airflow, which is called a tornado.

  At about 5: 15pm on July 3rd, a sudden tornado hit kaiyuan city, Liaoning Province, with a wind speed of 23m/s (magnitude 9) nearby. The tornado was formed by Jingouzi Town, passed through Xingkai Street and Kaiyuan Economic Development Zone, and lasted for 15 minutes to the south, then weakened into a low pressure.

  Tornadoes caused casualties, damaged houses and damaged power communication to varying degrees.

  At present, preliminary statistics have caused 6 deaths and more than 120 injuries. The specific situation is being counted. On-site rescue is being carried out in an orderly manner.

  How to save yourself when encountering a tornado? Sort out the escape skills when encountering a tornado, hoping to help more people!

What are the escape skills when encountering a tornado?

  Understand the signs of tornadoes. First of all, there will be some natural phenomena before tornadoes appear, often accompanied by black clouds, cumulonimbus clouds and lightning and thunder. In addition, cold wind, strong wind, heavy rain and hail are signs of tornadoes. To get to a safe place quickly, tornadoes are very terrible. The bottom of black clouds forms a funnel shape, and the wind speed can exceed 70 meters per second, which can roll up the car and run into the air. Different from the typhoon, with the swirling updraft, the objects on the ground along the way are also rolled up, and the rolled-up objects smash the glass of the building, causing the air pressure in the rented house to change sharply and the roof will be overturned.

  When we encounter a tornado, don’t panic. The following escape skills and precautions are to be remembered.

  1. When people are outdoors, it is important to hide in a strong building made of reinforced concrete. Never hide in garages, prefabricated buildings and black wooden storage sheds.

  2. When there are no buildings nearby, cover your head and neck with your hands and dive into ditches and depressions on the spot.

  3. When people are indoors, close the windows and draw the curtains, and don’t get close to the wall; Never be in danger because you concentrate on tornadoes; Located in the middle of the first floor in a two-story building; Rooms and toilets without windows are relatively safe for people; You can also cover your head and neck with your hands in the bathtub or under the table.

  Precautions: Once you notice a tornado approaching, you should immediately escape to a safe place.

How to save yourself when encountering a tornado?

  1. Identify tornadoes accurately

  Experts remind: Tornadoes occur in thunderstorms in summer and autumn, especially in the afternoon to dusk. When the roller cloud and funnel cloud were invented, it was a sign of a tornado, and it was usually accompanied by a hearty whistle! (10,000% of the time, because the speed at which the tornado began to move was annoying, it was careless. Don’t be busy making friends at this time!

  2. How to run after escape

  If you have enough time to escape, you must escape from the room. Be sure to stay away from dangerous houses and mobile homes, trees and telephone poles, and then retreat to the direction perpendicular to the movement of tornadoes (tornadoes usually don’t turn), and just hide in low-lying areas as a cover, and pay attention to cover your head.

  3. Accurate practice indoors

  When a tornado comes, if you can’t escape in the room, try to close some windows, but never close them all. The goal of this is to balance the pressure inside and outside the building. Just hide in the closet or basement, face the wall and hold your head down.

  4. What should I do in the car?

  Whether cars, bicycles or motorcycles are invented early, we must look at the vertical deviation from the wind belt. Otherwise, you should get off the bus immediately and find a suitable escape area around you (exaggerate again, pay attention to leaving trees and telephone poles). Don’t hide in or under the car, it is easy to be swept away.

  5. What is the best place to avoid tornadoes?

  A basements, bomb shelters, and the lowest floors of high-rise buildings that will not be swept away by the wind, flooded or blocked by equipment are the best places to avoid tornadoes.

  B. If you are in a school, hospital, workshop or shopping center, you should avoid the indoor room or lobby closest to the ground. Stay away from places with glass or wide roofs in the surrounding environment.

  C. When encountering a tornado in the open field, you can choose to lie down in low-lying places such as canals and river beds.

  D. warning: don’t go to halls, stacks, and temporary buildings to avoid such open and unsafe occasions.

  6, immediately leave the bridge, high ridge, coastal and dangerous houses, mobile homes. If there is no barrier around, you should lie flat in a low-lying place, but pay attention to waterproofing!

  Remind everyone that it is important to save your life, but never hurry, prevent crowding, help each other, and save yourself in an orderly manner. If you have valuables to transfer, you are advised to abandon them and run away.

Original title: How was the tornado caused? How to save yourself when encountering a tornado and escape skills when encountering a tornado.
Editor in charge: Li Xiaoling

The latest price of Changchun Baojun Yueye Automobile is 77,800 yuan, which is sold at a reduced price. The special discount is 0.2 million yuan, and the discount waits for no one.

[car home Changchun Preferential Promotion Channel] Specially reports that this popular small SUV is holding an unforgettable preferential activity in Changchun area. At present, the car buyers of Baojun Yueye are lucky enough to enjoy a cash discount of up to RMB 2,000, which brings tangible benefits to your car purchase plan. The starting price has dropped to 77,800 yuan, which is a good opportunity to buy a car with high cost performance. If you are interested in this model, be sure to click "Check the car price" in the quotation form to lock in this rare offer and realize your car dream as soon as possible.

长春宝骏悦也汽车最新价格7.78万,降价出售,特价打折优惠0.2万,优惠不等人

Bao Junyue is also a miniature SUV with great personality and fashion. Its front face design is unique and adopts a unique grille design, showing a youthful and energetic atmosphere. The overall style is simple and exquisite, the lines are smooth, and the body is small and smart, which leaves a deep impression. Whether commuting in the city or traveling on weekends, it can attract the attention of passers-by.

长春宝骏悦也汽车最新价格7.78万,降价出售,特价打折优惠0.2万,优惠不等人

Baojun Yueye’s side line design is unique, showing the integration of dynamic and exquisite. The body size is 3381mm*1685mm*1721mm, and the wheelbase is 2110mm, which makes the overall body proportion coordinated and the spatial layout reasonable. The front and rear wheel tracks are 1450mm, which ensures the driving stability and handling. The car is equipped with a set of 195/60 R15 tires with moderate width. With exquisite rim design, it not only strengthens the visual impact, but also ensures the grip and comfort during driving. On the whole, the side design of Baojun Yueye not only pays attention to practicality, but also does not lose its sense of movement and beauty.

长春宝骏悦也汽车最新价格7.78万,降价出售,特价打折优惠0.2万,优惠不等人

Baojun Yueye’s interior design is full of modernity and practicality. The interior style is exquisite and energetic, with simple lines and warm colors as the main features, creating a comfortable driving space. The steering wheel is made of leather material with good texture, which provides a good grip and supports manual adjustment up and down, which is convenient for the driver to adjust according to his personal needs. The center console is equipped with a 10.25-inch high-definition touch screen, which integrates multimedia system, navigation, telephone and air conditioning control, with convenient operation and clear display.

In terms of seats, the leather-like material is used, which is comfortable to touch. The front and rear, backrest and height adjustment are supported by the main and co-pilot seats to meet the riding needs of different passengers. Four USB/Type-C interfaces are also provided in the front row, which is convenient for passengers to connect electronic equipment and meet daily charging needs. In addition, the rear seats support proportional reclining, which provides additional convenience for the flexibility of the interior space.

长春宝骏悦也汽车最新价格7.78万,降价出售,特价打折优惠0.2万,优惠不等人

Bao Junyue is also equipped with an engine with moderate power performance, with a maximum power of 50 kW, providing a good driving force for the vehicle. At the same time, the maximum torque of this engine reaches 140 Nm, ensuring smooth performance in daily driving. This parameter configuration meets the balance requirements of fuel economy and drivability.

Summarizing the evaluation of the car owner in car home, Bao Junyue also won praise for its simple and fashionable interior design, with exquisite materials, rich configuration and exquisite craftsmanship, which makes people feel the coexistence of quality and practicality. Such a careful work undoubtedly provides an ideal choice for car owners who pursue fashion and comfortable driving experience.

The entrances and exits of 93 expressway toll stations in Jiangsu Province were temporarily closed in one or two directions.

  Cctv newsThe Jiangsu Provincial Department of Transportation announced today (12th) that the expressway operation in Jiangsu Province is generally stable. As of 9: 00 on August 12, the entrances and exits of 93 expressway toll stations in Nanjing, Wuxi, Xuzhou, Changzhou, Suzhou, Nantong, Lianyungang, Huai’ an, Yangzhou, Zhenjiang and Taizhou were temporarily closed in one or two directions.

  The specific closure situation is as follows:

  Nanjing (12): G25 Changshen Expressway Xinji Entrance and Lishui North Entrance, G40 Hushan Expressway Crossbeam North Entrance, G2503 Nanjing Ring Expressway Niigata, Ma ‘an, Crossbeam Entrance and Tianhou Village Entrance, G4221 Shanghai-Wuhan Expressway Dongping, Lukou South and Jiangjun Avenue Entrance, S55 Ningxuan Expressway Lishui Development Zone Entrance, S68 Liwu Expressway Entrance.

  Wuxi (5): G25 Changshen Expressway Dingshan Entrance, G4221 Huwu Expressway Xiake Entrance, S39 Jiangyi Expressway Heqiao Exit, S19 Tongxi Expressway Donggang and Anzhen Toll Station Exit;

  Xuzhou (7): G3 Jingtai Expressway Liuxin and Xuzhou West Exit, G30 Lianhuo Expressway Xinyi West Exit and Pizhou West Exit, G2513 Huaixu Expressway Suining West Exit, S49 Xinyang Expressway Malingshan Exit and S69 Jixu Expressway Shunhe Exit;

  Changzhou (7): G25 Changshen Expressway Caoshan Exit, G4221 Huwu Expressway Gehu Entrance and Maoshan Exit, S35 Fuli Expressway Shanghuang Toll Station Exit, S39 Jiangyi Expressway Wujin Economic Development Zone and Chunjiang Exit, and S68 Liwu Expressway Tangqiao Exit;

  Suzhou (1): entrance of Taicang New District of G15 Shenhai Expressway;

  Nantong (1): the southeast entrance of G40 Shanghai-Shaanxi Expressway;

  Lianyungang (10): G15 Shenhai Expressway Haitou, Luo Yang, Lianyungang North, Xinba and Guanyun North exits, G25 Changshen Expressway Ganyu South, Dapu, Songtiao, Guanyun West and Guannan South exits;

  Huai ‘an (9): G2 Beijing-Shanghai Expressway Huai ‘an North Exit, G25 Changshen Expressway Gaogou, Tieshan Temple Exit and Wulipai Exit, G1516 Yanluo Expressway Lingqiao and Shitang Exit, S49 Xinyang Expressway Huanghuatang and Xuyi North Exit, S22 Yanbang Expressway Dongyang Exit;

  Yangzhou (23): G2 Beijing-Shanghai Expressway Gaoyou, Zhenwu Entrance, G40 Shanghai-Shaanxi Expressway Jiangwang, Tangwang, Yangzhou Guangling, Hangji South, Daqiao Entrance, Jiangdu South Exit, Yizheng, Zaolinwan Entrance, G4011 Yangli Expressway Guazhou Entrance, S28 Qiyang Expressway Yangzhou North, Slender West Lake, Yangzhou West Entrance, Jiangdu North, Dinghuo, Yangzhou Taizhou Airport, Yangzhou.

  Zhenjiang (8): Jurong and Heyang exits of G42 Hurong Expressway, Jiangxi and Shangdang exits of G4011 Yangli Expressway Town, Tianwang exit of G4221 Huwu Expressway, Danyang North exit of S35 Fuli Expressway and East exit of Zhenjiang New District, and Gao Qiao exit of S39 Jiangyi Expressway;

  Taizhou (10): entrance and exit of Taizhou Toll Station of G2 Beijing-Shanghai Expressway, exit of Guangling and Jishi of G40 Shanghai-Shaanxi Expressway, exit of Qintong, Anfeng and Xinjie of G1515 Yanjing Expressway, exit of Zhouzhuang, Hailing, Yuduo and Dasi of S35 Fuli Expressway in Xinghua.

  As of 9: 00 on August 12, 25 provincial highways in Jiangsu Province were temporarily closed in one or two directions, as follows:

  Nanjing 10:

  1. The intersection K405+621 of Ning Gaoxin Passage Section of Jiangning G235 Xinhai Line is closed in both directions.

  2. The intersection of Jiangning S002 and S204 Ninggao Line K52+800 is closed in both directions towards the lake maturity direction.

  3. The intersection of Jiangning S002 and Jiangjun Avenue is closed in both directions towards Lukou.

  4. The junction of K41+097 Anhui on Jiangning S126 Ningdan Line is closed in both directions.

  5. At the junction of S204 and S002 in Jiangning, it is closed in both directions towards Lukou.

  6. The K15+200 Osborn section of Jiangning S204 Ninggao Line is closed in both directions (there is an exit in the upward direction).

  7. Jiangning S243 K82+600-86+100 is closed in both directions.

  8. The intersection of Jiangning S340 and Jiangjun Avenue is closed in the direction of Lukou.

  9. The ramp of Lishui S243 K76+850 Lishui Development Zone is closed in the direction of Xinhuai Avenue.

  10. Lishui S243 K79+200 double-yearned for the closing of the ramp crossing in the direction of S204.

  Yangzhou 8:

  1, G328 K302 Jiangdu entrance,

  2, S243 K2+950 Guazhou ferry,

  3, S462 K9+600 south along the Yangtze River,

  4, S61K7+600 and Hanjiang junction,

  5, S125 K43+900 and Yizheng junction,

  6, S356 K272+200 Jiangdu Hanjiang junction,

  7, S331 K100+270 (Yancheng Settings, Yancheng and Yangzhou border),

  8. S356 K272+600 Touqiao Town East Jiajiang Bridge West.

  Taizhou 5:

  1, G344 highway K135+400 xinghua city Qianduo Town and Yangzhou Gaoyou City junction,

  2, G523 highway K20+031 Gaogang ferry (border with Zhenjiang),

  3, S351 highway K116 xinghua city development zone and Yangzhou Gaoyou junction,

  4, S352 highway K101+100 xinghua city Chenbao Town and Yangzhou Jiangdu District junction,

  5. The downward direction of G328 Highway K274+550 is the boundary of Yangzhou, Kowloon.

  Huaian 2:

  1, S348 K196+500 to Hongze city direction,

  2. S350 at the intersection of S350 and S247 is heading for Hongze.

The day before taking over the rotating presidency of the European Union, the Hungarian Prime Minister announced the formation of a new party group of the European Parliament.

[Text/Observer Network Chen Sijia] According to the Hungarian National newspaper, on June 30, local time, just the day before Hungary officially took over the rotating presidency of the European Union, Hungarian Prime Minister Orban announced that he would cooperate with Austrian and Czech right-wing parties to form a new party group in the European Parliament. The goal of the party group is to become the largest right-wing alliance in Europe, thus "changing European politics".

According to the report, Orban met with Andrei Babiche, leader of the Czech Disgruntled Citizen Action Party, and Herbert Kickel, leader of the Austrian Liberal Party, in Vienna, Austria, and the three of them signed an agreement to form a "Patriots for Europe" party group.

Orban said at a joint news conference that the EU economy is in crisis, facing the threat of terrorism, illegal immigration and the risk of escalating the conflict between Russia and Ukraine. He accused the EU leadership of making a wrong decision, which led to the loss of competitiveness of the European economy. "The European people want peace, order and development, but the Brussels elite has only brought war, immigration and stagnation."

Orban said that the new party group was formed to change European politics. "Today, three political parties are united: the most powerful Austrian party, the most powerful Czech party and the most powerful Hungarian party. We have the responsibility to start this new platform and new faction. Our goal is to become the most powerful right-wing alliance in European politics. "

Czech "Dissatisfied Citizens Action Party"Leader Babiche, Austrian Liberal Party leader Kickel and Hungarian Prime Minister Orban signed an agreement to form a new party group (video screenshot).

Kickel also delivered a speech at the news conference. He described the "European Patriots" party group as "a powerful core of change in central Europe" with the goal of ensuring a "better future" for Europe. Kickel also announced that the new party group will appear at the first meeting of the new European Parliament on July 16th, local time, seeking to initiate a "political change".

Babiche, on the other hand, said that the agenda of the "European Patriots" party group will be linked with the three priorities of protecting sovereignty, cracking down on illegal immigrants and revising the green agreement. He believes that the EU must formulate laws and regulations to protect the borders of member States and stop illegal immigration, and revise the green agreement in a more balanced way to ensure that environmental protection policies will not endanger the EU’s economic development and competitiveness.

Babiche said that the new party group wants to build a "Europe composed of independent nation States" instead of a "Brussels-led Federation". "We are open to cooperation with all like-minded organizations and individuals."

In the European Parliament elections held in June, the multinational right-wing parties in the European Union performed strongly. Among them, the Hungarian ruling party, the Youth League led by Orban, won 11 seats in the European Parliament, the largest opposition party in the Czech Republic, the Dissatisfied Civil Action Party, won 7 seats, and the Austrian Liberal Party won 6 seats, all of which were the political parties with the highest votes in their respective countries.

However, the European News Channel pointed out that the "European Patriot" party group still needs the support of at least four political parties in other countries before it can be recognized as a party group in the European Parliament.

On July 1, local time, Hungary officially took over the rotating presidency of the European Union for a term of six months. During this period, Hungary will host the EU meeting and set the EU’s political agenda.

The Hungarian National newspaper said that Orban put forward the slogan of "making Europe great again", and listed seven priorities: improving the EU’s economic competitiveness, strengthening the defense policy, promoting the EU’s enlargement process, curbing illegal immigrants, reshaping the "cohesion fund" aimed at narrowing the gap between the rich and the poor, promoting the "farmer-oriented agricultural policy" and meeting the population challenge.

Ianos Boca, Hungarian Minister of EU Affairs, told Hungarian media on June 30th that improving European competitiveness will be the main topic of concern during Hungary’s presidency. Hungary hopes to build a European capital market that can promote infrastructure and energy links, and formulate European industrial policies aimed at achieving key goals such as green transformation.

Boca also pointed out that when Hungary holds the rotating presidency, the European Parliament, the European Commission and other institutions are being reorganized, so Hungary will also strive to ensure the smooth operation of EU institutions. "As long as Hungary, as the presidency, can show the changes expected by European citizens according to the results of the European Parliament elections while ensuring the transition of EU institutions, then Hungary is successful."

This article is an exclusive manuscript of Observer. It cannot be reproduced without authorization.

Tear off the mask of free competition and curb China’s technological development. How many "devils" are hidden in the US "Chip Act"?

  [Global Times reporter Yuan Jirong] In order to suppress and contain the rising China science and technology and safeguard American hegemony, Washington has increasingly turned to the core of the digital economy — — In the field of chips. On August 15th, the US Department of Commerce implemented export control on EDA software known as "the mother of chips". Previously, the United States had promulgated the Chip and Technology Act of 2022 (hereinafter referred to as the "Chip Act") on July 28th. The purpose of this bill is to cut off the supply of advanced technology, equipment and materials for chip manufacturing to China, accelerate the return of the chip industry to the United States through subsidies, cut off the contact between China’s chip industry and the world, and reshape the supply chain pattern of the global chip industry chain. Obviously, this is a wishful plan of the United States. So how many "devils" are hidden in the "Chip Act" of the United States? Our reporter conducted an interview and investigation.

  In the five sub-chains, where do Chinese and American enterprises occupy?

  The main contents of the "Chip Act" in the United States include three items: one is to provide 52.7 billion US dollars of financial support to the semiconductor industry; The second is to provide enterprises with a 25% investment tax credit of about $24 billion; The third is to allocate about 200 billion US dollars to support cutting-edge technologies such as artificial intelligence, robotics and quantum computing. The United States is trying to attract enterprises to set up factories in the United States, so as to concentrate the advanced process (below 28 nm) chip manufacturing industry in the United States, to confront China’s challenges in the semiconductor field, and to safeguard the technological hegemony of the United States. According to industry data, in 1990, the United States accounted for 37% of the global semiconductor manufacturing industry, and in 2020, this proportion dropped to 12%.

  In the related statement issued by the White House, the purpose of the "Chip Act" includes reducing costs, creating jobs, strengthening the supply chain and so on, so as to compete with China. To this end, the bill requires the establishment of four funds: the "American chip fund" totals 50 billion US dollars, of which 39 billion US dollars is used to encourage chip production and 11 billion US dollars is used to subsidize chip research and development; The "US Chip Defense Fund" has a total of 2 billion US dollars to subsidize the production of key chips related to national security, which will be allocated by the US Department of Defense in stages from 2022 to 2026; The "American Chip International Technology Security and Innovation Fund" has a total of 500 million US dollars to support the establishment of a safe and reliable semiconductor supply chain; The "American Chip Labor and Education Fund" has a total of 200 million US dollars to cultivate talents in the semiconductor industry.

  As the largest chip market in the world, China consumes about 3/4 of the chips in the world. But in the global chip industry chain, China is in the middle and lower reaches. Chip industry has its unique internal structure and industrial characteristics, and its industrial chain is divided into five sub-chains. The first is design. The largest chip design company in the world is ARM in Britain, EDA in the United States occupies a monopoly position in software design, and the design capability of Huawei Hisilicon can reach 7 nanometers. The second is manufacturing, including finished products and semi-finished products. Among them, semi-finished products generally refer to wafers, and high-purity wafers are basically monopolized by Japanese companies; Chip products are made on the basis of wafers, and the international output of SMIC is currently the fifth in the world. The third is packaging testing, which is basically labor-intensive, and the gap between China and the world is not big. The fourth is equipment production. The most sophisticated EUV mask aligner is ASML, the Netherlands, which is the only enterprise that can provide 7 nm process mask aligner. The equipment manufacturers that produce wafers are mainly in Japan, and companies such as Mitsubishi and Sony are dominant. Shanghai Microelectronics has been able to produce equipment for making 28 nm chips. The fifth is auxiliary materials. Including photoresist, mask, target, packaging substrate, etc., these materials are still facing bottlenecks in China enterprises.

  Geng Bo, deputy secretary-general of the Third Generation Semiconductor Industry Technology Innovation Strategic Alliance, told the Global Times reporter that "the layout of key patents involving upstream advanced process technology, some key raw materials, equipment and spare parts consumables is still not perfect". At present, there is a severe trade deficit in China’s integrated circuit industry, and some high-end chips are not completely self-sufficient. Take memory chips as an example. At present, American products account for half of the global market, South Korea accounts for about 25%, Japan accounts for 10%, Europe accounts for 8%, and China accounts for 3%.

  Killing is mainly in the manufacturing process.

  Recently, IC Insights, a well-known semiconductor research institution, released a report. In 2021, the chip scale consumed in China was about 186.5 billion US dollars, but the chip manufactured in Chinese mainland was only 31.2 billion US dollars, accounting for only 16.7%. The "Chip Act" of the United States mainly focuses on the following aspects, with the intention of strangling China’s chip industry in its infancy.

  First, the technology, equipment and materials below 28 nm are blocked from China. Han Xiaomin, general manager of Jiwei Consulting, told reporters that the restrictions of the chip bill are mainly reflected in two aspects: First, supply chain resources such as equipment and materials related to advanced manufacturing are continuously prohibited from being given to local enterprises in China, and the research and development progress of China enterprises in the field of advanced manufacturing is suppressed; Second, chip companies supported by the Chip Act are required not to invest in advanced technology in Chinese mainland and continue to split the China market and the global supply system. Although the restrictions of the "Chip Act" mainly start from the manufacturing link, it will cooperate with a series of other restrictions. For example, EDA tools involving GAA process have just been banned from being used by China enterprises recently; Restrict American companies from providing China with the equipment needed to manufacture advanced chips; Pressure the Dutch government to ban ASML from selling deep ultraviolet mask aligner to China.

  Secondly, through subsidies, it is forbidden for companies receiving US federal funds to significantly increase production of advanced process chips in China for a period of 10 years. Companies that violate the ban or fail to correct the violation may need to refund the federal grant in full. According to the BBC, in the past, all American equipment manufacturers received a letter from the US Department of Commerce, informing them not to supply China with equipment for manufacturing chips of 14 nanometers or less. Tim Archer, chairman and CEO of American chip equipment manufacturer Panlin Semiconductor, said at the latest financial report that the scope of US technology export control to China will be further extended to foundries that produce chips below 14 nanometers.

  Before and after the "Chip Act" was signed, under the high-pressure atmosphere, many American semiconductor companies have announced that they will expand their investment in their own country. On August 9th, Micron announced that it will invest 40 billion dollars to make chips in the United States by 2030, and this action will be supported by the Chip Act. Reuters reported on the 8th that Qualcomm has agreed to purchase an additional $4.2 billion worth of semiconductor chips from Gexin’s new york factory, bringing its total purchase to $7.4 billion by 2028.

  Finally, we should promote the establishment of the "Four-Party Alliance of Chips" to further restrict the development of chips in China. This is a chip industry alliance between the United States, Japan, South Korea and Taiwan Province, which is intended to monopolize the high-end chip industry. It wants to integrate the chip manufacturing industry of American allies and set up a chip supply chain in the United States to exclude competitors.

  China’s Countermeasures

  Industry experts believe that in the short term, the "Chip Act" involves high-end OEM of advanced manufacturing technology, and memory has a great impact on China. However, in the long run, it is the consensus of domestic industry to carry out localization in related fields, and the restrictions of the bill can only accelerate this process. Geng Bo said that the upstream semiconductor equipment and materials will benefit from the continuous expansion of production and the acceleration of localization in China Wafer Factory. In view of the macro-policy blessing of localization and the uncertainty of international situation and supply chain security, China semiconductor industry should do a good job in top-level design and overall layout, increase policy support, strengthen international cooperation outside the United States, enlarge and strengthen the head enterprise, increase the training of industry talents and discipline construction, and strive to establish a certain closed-loop supply capacity in the industrial chain to prevent the recurrence of "core shortage tide".

  At the same time, for the United States, relying on a "chip bill" cannot reshape the glory of the local chip industry, and it is even more difficult to rebuild the manufacturing industry chain. Some industry experts said that the global "chip shortage" has been gradually eased this year, and there has even been a surplus in chip production, and many chips are being sold at reduced prices. This means that the chip industry is not a promising industry at least for the moment. Market investors are also confirming this judgment. After the release of the "Chip Act", the share prices of major semiconductor companies in the United States fell due to the decline in demand for early warning in the industry.

  Han Xiaomin said that the "Chip Act" can alleviate the strategic anxiety of the United States by attracting leading enterprises to set up factories in the United States through subsidies. However, it is not optimistic that the United States will truly become an advanced technology manufacturing base. Some experts believe that although China has not broken through the high-end chip manufacturing technology for the time being, it has chip factories accounting for half of the world’s total, and the "Chip Act" of the United States will promote Chinese enterprises to break through the technology. The domestic manufacturing industry in the United States is hollow and lacks talents, and it is impossible to form independent chip production capacity in a short time. According to the estimation of the Boston Consulting Group and other institutions, if the United States adopts the policy of "hard decoupling technology" from China, it may cause American semiconductor enterprises to lose 18% of the global market share and 37% of the revenue, and reduce 15,000 to 40,000 high-skilled jobs. This is tantamount to luring domestic enterprises away from the China market with a drop in the bucket subsidy.

China FAW’s total sales in January exceeded 296,800 vehicles, up 54.2% year-on-year.

On February 5th, China FAW announced today that the group’s total sales in January exceeded 296,800 vehicles, up 54.2% year-on-year.

. The total sales volume of the new Red Flag H5 and the new Red Flag HS5 increased by 178% year-on-year. The sales volume of the new Red Flag H5 ranked first in China brand B luxury fuel car, and the sales volume of the new Red Flag HS5 ranked first in China brand B luxury fuel SUV.

Jiefang brand has a terminal share of 24.3% in the heavy truck market, ranking first in the industry, 32.8% in the NG tractor market and 33.9% in the diesel coal transportation market.

In January, Pentium brand achieved more than 10,000 wholesale and terminal retail sales, with wholesale sales increasing by 86% and terminal retail sales increasing by 121%. Among them, the terminal retail sales of the main model Pentium B70 are stable at more than 5,000 vehicles.

It should be noted that the specific sales volume of FAW-Volkswagen and FAW-Toyota has not been mentioned officially.

In the deeds of January, China FAW also mentioned that the Liberation Power Changchun Super Factory was officially put into production, the 100 millionth battery of Times FAW was rolled off the assembly line, the first SOP white body of FAW-Volkswagen VW491 project was rolled off the assembly line, and the first phase of FAW Foday new energy power battery was successfully put into production in Changchun.

How to import soda music into local music How to import soda music into local music [Detailed explanation]

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  Has the relevant introduction brought by Xiaobian solved these doubts for everyone? Interested users come to IT Encyclopedia.

Learn from him-strengthen cultural self-confidence and inspire national spirit.

  CCTV News:Culture is the ideological guidance, spiritual support, moral education and knowledge nurturing of a country and a nation, and it is also an important symbol that distinguishes a country and a nation from other countries and nations. Extensive and profound excellent traditional culture, distinctive and unique revolutionary culture, and advanced socialist culture have consolidated the foundation of cultural construction and laid a strong foundation for cultural self-confidence.

  Since the 18th National Congress of the Communist Party of China, General Secretary of the Supreme Leader has mentioned "cultural self-confidence" many times, and made many profound expositions from the overall situation of Socialism with Chinese characteristics’s cause, which has injected more basic, deeper and more lasting power into the great cause of Socialism with Chinese characteristics. General Secretary Supreme Leader’s exposition on cultural self-confidence is very rich, profound and incisive, which is an organic part of Supreme Leader’s Socialism with Chinese characteristics Thought in the new era. Today, we have specially compiled the important exposition of the Supreme Leader General Secretary on cultural self-confidence for everyone to learn.

  fine traditional Chinese culture

  [From, casting, rooting]

  Socialism with Chinese characteristics culture, which originated from the excellent traditional Chinese culture nurtured by the 5,000-year civilization history of the Chinese nation, was cast in the revolutionary culture and advanced socialist culture created by the Party leading the people in revolution, construction and reform, and was rooted in the great practice of Socialism with Chinese characteristics.

  — — On October 18, 2017, the report was published in The 19th National Congress of the Communist Party of China.

  On October 18, 2017, the Supreme Leader made a report at the The 19th National Congress of the Communist Party of China.

  "Very proud, very confident"

  In every historical period, the Chinese nation has left countless immortal works. From the Book of Songs, Chu Ci, Han Fu, to Tang Poetry, Song Ci, Yuan Qu, Ming and Qing novels, etc., they have jointly created a splendid star river of China’s literary history. The Chinese nation’s literary and artistic creativity is so strong and its achievements are so brilliant. The Chinese nation is known for its cultural self-confidence. We should be extremely proud of it and feel extremely confident about it.

  — — On November 30, 2016, he delivered a speech at the opening ceremony of the 10th National Congress of China Federation of Literary and Art Circles and the 9th National Congress of China Writers Association.

  [Important basis, content and contribution]

  A large number of great works in ancient China contain rich contents of philosophy and social sciences and wisdom of governing the country, which provides an important basis for the ancients to understand and transform the world, and also provides important contents for Chinese civilization and makes great contributions to human civilization.

  — — Speech at the Symposium on Philosophy and Social Sciences on May 17, 2016

  [Creation and Continuation, Roots and Soul]

  China has a long history and a broad civilization. The excellent Chinese traditional culture created and continued by the Chinese nation in thousands of years of history is the root and soul of the Chinese nation.

  — — On December 20, 2014, speech at the celebration of the 15th anniversary of Macao’s return to the motherland and the inauguration ceremony of the fourth government of Macao Special Administrative Region.

  Revolutionary culture

  [Maintain revolutionary spirit and revolutionary fighting spirit]

  To achieve the prosperity and long-term stability of the Party and the country, all comrades in the Party must maintain the revolutionary spirit and fighting spirit, and have the courage to carry forward the great social revolution that our Party led the people for 97 years. We must never be proud of victory, never slack off because of achievements, and never shrink back because of difficulties, and strive to make Socialism with Chinese characteristics show a stronger and more convincing force of truth.

  — — On January 5, 2018, he delivered an important speech at the opening ceremony of the seminar on studying and implementing the spirit of the 19 th Party Congress

  [Inheriting the Red Gene]

  We must inherit the red genes of the people’s army, strive to cultivate revolutionary soldiers with soul, ability, blood and morality in the new era, and always maintain the nature, purpose and true colors of the people’s army. We should inherit and carry forward the glorious tradition and historical experience of our party and people’s army, and make continuous progress on the road of upholding and developing Socialism with Chinese characteristics.

  — — Speech during the inspection tour in Xuzhou City, Jiangsu Province from December 12 to 13, 2017

  From December 12 to 13, 2017, the Supreme Leader visited Xuzhou City, Jiangsu Province. On the afternoon of the 12th, the Supreme Leader cordially visited workers’ representatives such as model workers and technical experts in Xugong Group Heavy Machinery Co., Ltd., and encouraged them to strive for everyone’s brilliance in the struggle to realize the Chinese dream.

  [Roots of our Party]

  The Red Boat in Nanhu, Jiaxing, a major meeting place of the Party in Shanghai, is the place where our Party dreams to set sail. Our party was born here, went to war here, and came to power throughout the country from here. This is the root vein of our party.

  — — On October 31, 2017, I gave a speech when I visited the site of the First Congress of the Communist Party of China.

  [Infiltrate into blood and heart]

  An inch of mountains and rivers, an inch of blood, a hot land and a soul. Looking back on the past bonfire years, the people of Jinzhai have made great contributions to the revolutionary cause of China with fearless sacrifice. We will continue to follow the footsteps of the revolutionary predecessors and pass on the red mountains and rivers from generation to generation. Revolutionary traditional education should start with dolls, pay attention to both knowledge infusion and emotional cultivation, so that the red gene can seep into the blood and heart, and guide the majority of teenagers to establish a correct world outlook, outlook on life and values.

  — — On April 24, 2016, I made a speech during my investigation in Anhui.

  advanced socialist culture

  [Culture makes the country prosperous and the nation strong]

  Culture is the soul of a country and a nation. Culture makes the country prosperous and the nation strong. Without a high degree of cultural self-confidence and cultural prosperity, there would be no great rejuvenation of the Chinese nation. We should adhere to the road of cultural development in Socialism with Chinese characteristics, stimulate the cultural innovation and creativity of the whole nation, and build a socialist cultural power.

  Socialism with Chinese characteristics culture, which originated from the excellent traditional Chinese culture nurtured by the 5,000-year civilization history of the Chinese nation, was cast in the revolutionary culture and advanced socialist culture created by the Party leading the people in revolution, construction and reform, and was rooted in the great practice of Socialism with Chinese characteristics. To develop Socialism with Chinese characteristics culture is to take Marxism as a guide, stick to the Chinese cultural stance, base on the reality of contemporary China and combine the conditions of the present era to develop a national, scientific and popular socialist culture facing modernization, the world and the future, and promote the coordinated development of socialist spiritual civilization and material civilization. We must persist in serving the people and socialism, let a hundred flowers blossom and a hundred schools of thought contend, and persist in creative transformation and innovative development, and constantly create new glories of Chinese culture.

  — — On October 18, 2017, the report was published in The 19th National Congress of the Communist Party of China.

  [The most reason to be confident]

  To persist in Do not forget your initiative mind and continue to advance, we must adhere to Socialism with Chinese characteristics’s road confidence, theoretical confidence, institutional confidence and cultural confidence, unswervingly adhere to the Party’s basic line, and constantly push forward the great cause of Socialism with Chinese characteristics.

  The whole party should be confident in road, theory, system and culture. In today’s world, if any political party, country or nation can be confident, the Communist Party of China (CPC), People’s Republic of China (PRC) and the Chinese nation have the most reasons to be confident. With the courage of "self-confidence in life for 200 years, we will be able to hit three thousand miles with water", we can face all difficulties and challenges without fear, and we can unswervingly open up new horizons and create new miracles.

  — — On July 1, 2016, speech at the conference to celebrate the 95th anniversary of the founding of the Communist Party of China (CPC).

  [Strengthening cultural self-confidence and inspiring national spirit with literature and art]

  I hope everyone will strengthen their cultural self-confidence and inspire the national spirit with literature and art. To realize the great rejuvenation of the Chinese nation, we must strengthen Socialism with Chinese characteristics’s road confidence, theoretical confidence, institutional confidence and cultural confidence. To create excellent works with distinctive national characteristics and personality, we must have a deep understanding of the profound Chinese culture and a high degree of cultural self-confidence. The vast number of literary and art workers should be good at extracting the essence and energy from the treasure house of Chinese culture, maintain high confidence in their own cultural ideals and values, maintain high confidence in their own cultural vitality and creativity, and make their works become spiritual forces that inspire the people of China and the Chinese nation to keep moving forward.

  — — On November 30, 2016, he delivered a speech at the opening ceremony of the 10th National Congress of China Federation of Literary and Art Circles and the 9th National Congress of China Writers Association.

  Producer/Zhen Chen 

  Editor/Tang Jinggang

  Editor/Zhao Jin

  American editor/Wu Yanni

  Editor/Cui Qi

  (This article comes from WeChat WeChat official account’s "No.1 Online", which is a new media platform for promoting major themes of CCTV, and is operated by the Publicity and Coordination Department of the editorial office. )

New brand, new experience, test drive Auchan COS 1 (Kesai)

Model picture Basic parameter Changan Auchan Cosai 2018 1.5T Auto Smart 7 Block Changan Auchan Cosai 2018 1.5T automatic 7-seat Changan Auchan Cosai 2018 1.5T automatic sense 7 seats Changan Auchan Cosai 2018 1.5T automatic wonderful 6-seat Manufacturer’s guide price 145,800 109,800 119,800 132,800 Dealer quotation manufacturer Changan automobile Changan automobile Changan automobile Changan automobile grade Medium SUV Medium SUV Medium SUV Medium SUV Energy type petrol petrol petrol petrol Environmental protection standard Guo v Guo v Guo v Guo v Time to market 2018.09 2018.09 2018.09 2018.09 Maximum power (kW) 131 131 131 131 Maximum torque (n m) 265 265 265 265 engine 1.5T 178 HP L4 1.5T 178 HP L4 1.5T 178 HP L4 1.5T 178 HP L4 gearbox 6-speed manual integration 6-speed manual integration 6-speed manual integration 6-speed manual integration Length * width * height (mm) 4830*1868*1775 4830*1868*1775 4830*1868*1775 4830*1868*1775 Body structure 5-door 7-seat SUV 5-door 7-seat SUV 5-door 7-seat SUV 5-door 6-seat SUV Maximum speed (km/h) – – – – Official 0-100km/h acceleration (s) – – – – Measured 0-100km/h acceleration (s) 12.37 – – – Measured braking at 100-0km/h (m) 42.94 – – – NEDC comprehensive fuel consumption (L/100km) 7.2 7.2 7.2 7.2 Measured fuel consumption (L/100km) 11.2 – – – Vehicle warranty Three years or 100 thousand kilometers Three years or 100 thousand kilometers Three years or 100 thousand kilometers Three years or 100 thousand kilometers bodywork Changan Auchan Cosai 2018 1.5T Auto Smart 7 Block Changan Auchan Cosai 2018 1.5T automatic 7-seat Changan Auchan Cosai 2018 1.5T automatic sense 7 seats Changan Auchan Cosai 2018 1.5T automatic wonderful 6-seat Length (mm) 4830 4830 4830 4830 Width (mm) 1868 1868 1868 1868 Height (mm) 1775 1775 1775 1775 Wheelbase (mm) 2800 2800 2800 2800 Front track (mm) – – – – Rear wheel track (mm) – – – – Body structure SUV SUV SUV SUV Number of vehicles (units) five five five five Number of seats (units) seven seven seven six Tank volume (l) – – – – Trunk volume (l) – – – – Curb quality (kg) 1745 1745 1745 1745 engine Changan Auchan Cosai 2018 1.5T Auto Smart 7 Block Changan Auchan Cosai 2018 1.5T automatic 7-seat Changan Auchan Cosai 2018 1.5T automatic sense 7 seats Changan Auchan Cosai 2018 1.5T automatic wonderful 6-seat Engine model JL476ZQCF JL476ZQCF JL476ZQCF JL476ZQCF Displacement (mL) 1499 1499 1499 1499 Displacement (l) 1.5 1.5 1.5 1.5 Air intake form turbocharge turbocharge turbocharge turbocharge Cylinder arrangement form L L L L Number of cylinders (each) four four four four Number of valves per cylinder (units) four four four four admission gear DOHC DOHC DOHC DOHC Maximum horsepower (Ps) 178 178 178 178 Maximum power (kW) 131 131 131 131 Maximum power speed (rpm) – – – – Maximum torque (n m) 265 265 265 265 Maximum torque speed (rpm) – – – – Fuel form petrol petrol petrol petrol Fuel label No.92 No.92 No.92 No.92 Oil supply mode Direct injection Direct injection Direct injection Direct injection Cylinder head material aluminium alloy aluminium alloy aluminium alloy aluminium alloy Cylinder block material aluminium alloy aluminium alloy aluminium alloy aluminium alloy Environmental protection standard Guo v Guo v Guo v Guo v gearbox Changan Auchan Cosai 2018 1.5T Auto Smart 7 Block Changan Auchan Cosai 2018 1.5T automatic 7-seat Changan Auchan Cosai 2018 1.5T automatic sense 7 seats Changan Auchan Cosai 2018 1.5T automatic wonderful 6-seat Number of gears six six six six Gearbox type AutomATic manual transmission (at) AutomATic manual transmission (at) AutomATic manual transmission (at) AutomATic manual transmission (at) abbreviation 6-speed manual integration 6-speed manual integration 6-speed manual integration 6-speed manual integration Chassis steering Changan Auchan Cosai 2018 1.5T Auto Smart 7 Block Changan Auchan Cosai 2018 1.5T automatic 7-seat Changan Auchan Cosai 2018 1.5T automatic sense 7 seats Changan Auchan Cosai 2018 1.5T automatic wonderful 6-seat type of drive Precursor Precursor Precursor Precursor Front suspension type mcphersonindependent suspension mcphersonindependent suspension mcphersonindependent suspension mcphersonindependent suspension Rear suspension type Multi-link independent suspension Multi-link independent suspension Multi-link independent suspension Multi-link independent suspension Type of assistance Electric booster Electric booster Electric booster Electric booster Car body structure Bearing type Bearing type Bearing type Bearing type Wheel braking Changan Auchan Cosai 2018 1.5T Auto Smart 7 Block Changan Auchan Cosai 2018 1.5T automatic 7-seat Changan Auchan Cosai 2018 1.5T automatic sense 7 seats Changan Auchan Cosai 2018 1.5T automatic wonderful 6-seat Front brake type Ventilated disc Ventilated disc Ventilated disc Ventilated disc Rear brake type disc-type disc-type disc-type disc-type Parking brake type electrical parking brake electrical parking brake electrical parking brake electrical parking brake Former tyre size 225/60 R18 225/65 R17 225/65 R17 225/60 R18 After tyre size. 225/60 R18 225/65 R17 225/65 R17 225/60 R18 Spare tire specification Non-Full-Size full-scale full-scale Non-Full-Size